Project Objectives
O1. Produce and characterize a pH-dependent micellar assembly of functionalized copolymer blocks and targeted delivery of AXL inhibitor to target Her positive breast cancer tumors.
O2. Produce a range of complex functionalized and loaded nanostructured assemblies with different pH stability.
O3. Study in vitro biological interactions between simple/functionalized nanostructured micelles and appropriate breast cancer (BC) cell lines.
O4. Evaluate the biodistribution of pH sensitive nanostructures.
Project Workpackages
WP1. Management
WP2. Design, development, characterization and production of polymer-based pH sensitive modules
WP3. In vitro studies of pH sensitive nanostructures
